Neomycin sulphate is an antibiotic medication used to treat various bacterial infections.
## Properties and Uses
1. *Antibiotic*: Neomycin sulphate is an aminoglycoside antibiotic that works by inhibiting protein synthesis in bacteria.
2. *Infections treated*: It's used to treat infections caused by gram-negative bacteria, including urinary tract infections, skin infections, and eye infections.
3. *Topical applications*: Neomycin sulphate is often used in topical applications, such as creams, ointments, and eye drops.
## Mechanism of Action
1. *Inhibiting protein synthesis*: Neomycin sulphate works by binding to the bacterial ribosome, inhibiting protein synthesis and ultimately leading to bacterial death.
2. *Bactericidal*: It's a bactericidal antibiotic, meaning it kills bacteria directly.
## Safety and Handling
1. *Ototoxicity*: Neomycin sulphate can cause ototoxicity (hearing loss) and nephrotoxicity (kidney damage) with prolonged use or high doses.
2. *Allergic reactions*: Some people may be allergic to neomycin sulphate, and severe allergic reactions can occur.
3. *Side effects*: Common side effects include skin irritation, redness, and itching.
## Regulatory Status
1. *Prescription medication*: Neomycin sulphate is a prescription medication, available only with a doctor's prescription.
2. *Regulatory approval*: It's approved by regulatory agencies, such as the US FDA, for use in treating bacterial infections.
